Volume 1 ; Issue 1 ; in Month : Jan-June (2024) Article No : 106
Beniwal A, Mathur R, Pareek B, et. al.

Abstract

Background: Liver cirrhosis is an escalating health issue, and the death rate associated with this illness is fast rising among both males and females. In the initial stages, cirrhosis typically does not produce noticeable signs or symptoms. However, as liver function declines, many indications and symptoms become evident, such as fatigue, nausea, unintentional weight loss, jaundice, gastrointestinal bleeding, severe itching, and swelling in the legs and abdomen. Liver illnesses are significantly influenced by micronutrients. Magnesium is the second most prevalent ion found within cells and the fourth most prevalent positively charged ion in the body. Objective: This study aimed to analyze the connection between magnesium levels and the severity of liver cirrhosis and its consequences. The significance of trace elements, such as magnesium, in the etiology of liver cirrhosis is not yet fully known. Materials and Methods: This study was a hospital-based case-control observational study. The study was carried out in the Central Lab, Department of Biochemistry, SMS Medical College & associated Hospitals in Jaipur. This study included 92 patients diagnosed with liver cirrhosis and a sample size of 92 healthy controls. Result: The average serum magnesium levels of the patients (1.13 ± 0.21) are lower than those of the controls (2.07 ± 0.27). Conclusion: The study revealed a statistically significant drop in magnesium levels in liver cirrhotic patients compared to the control group. Utilizing these uncomplicated and economical biochemical parameters may serve as biomarkers for the early diagnosis of liver cirrhosis and aid in the identification of people with this condition.

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